Summary
Impact: Security Feature Bypass. Microsoft rating: Important. Not known to be exploited — Exploitation Less Likely. Customer action: Required.
Details
There are multiple update packages available for some of the affected software. Do I need to install all the updates listed in the Security Updates table for the software?
Yes. Customers should apply all updates offered for the software installed on their systems. If multiple updates apply, they can be installed in any order.
What kind of security feature could be bypassed by successfully exploiting this vulnerability?
An attacker who successfully exploits this vulnerability could bypass Windows Defender Application Control (WDAC) enforcement. This could lead to the ability to run unauthorized applications on target systems.
According to the CVSS metric, user interaction is required (UI:R). What interaction would the user have to do?
An attacker must send a user a malicious Office file and convince them to open it.
Is the Preview Pane an attack vector for this vulnerability?
No, the Preview Pane is not an attack vector.
Security updates
https — https://docs.microsoft.com/en-us/officeupdates/microsoft365-apps-security-updates
16.0.5483.1001 — https://support.microsoft.com/help/5002675
16.0.5483.1000 — https://support.microsoft.com/help/5002595
Vulnerabilities 1
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High 7.1
Microsoft Office Security Feature Bypass Vulnerability
Microsoft Office Security Feature Bypass Vulnerability
Revision history
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#2
Added an FAQ to indicate that the Preview Pane is not affected for this CVE. This is an informational change only.
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#1
Information published.
References
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CVE-2025-21346 Microsoft Office Security Feature Bypass Vulnerability - HTML
https://msrc.microsoft.com/update-guide/vulnerability/CVE-2025-21346
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Microsoft Exploitability Index
https://www.microsoft.com/en-us/msrc/exploitability-index?rtc=1
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Microsoft Support Lifecycle
https://support.microsoft.com/lifecycle
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Common Vulnerability Scoring System
https://www.first.org/cvss