Windows Mark of the Web Security Feature Bypass Vulnerability

According to the CVSS metrics, successful exploitation of this vulnerability could lead to some loss of integrity (I:L) and some loss of availability (A:L). What does that mean for this vulnerability?
An attacker can craft a malicious file that would evade Mark of the Web (MOTW) defenses, resulting in a limited loss of integrity and availability of security features such as Protected View in Microsoft Office, which rely on MOTW tagging.

How could an attacker exploit the vulnerability?
To exploit this vulnerability, an attacker could host a file on an attacker-controlled server, then convince a targeted user to download and open the file. This could allow the attacker to interfere with the Mark of the Web functionality.
Please see Additional information about Mark of the Web for further clarification

Security updates
10.0.17763.8880 — https://support.microsoft.com/help/5094123
10.0.20348.5256 — https://support.microsoft.com/help/5094128
10.0.19044.7417 — https://support.microsoft.com/help/5094127
10.0.26100.32995 — https://support.microsoft.com/help/5094125
10.0.26200.8655 — https://support.microsoft.com/help/5094126
10.0.22631.7219 — https://support.microsoft.com/help/5093998
10.0.28000.2269 — https://support.microsoft.com/help/5095051
10.0.14393.9234 — https://support.microsoft.com/help/5094122
6.3.9600.23228 — https://support.microsoft.com/help/5094041