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High · 7.8 Public exploit CVE-2025-50675 EUVD-2025-23937GHSA-j2h6-xj8p-656p

GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The d…

Published Aug 7, 2025 · Updated Aug 8, 2025 · Assigned by mitre

Description

GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The directory is accessible with full read, write, and execute permissions for all users, allowing unprivileged users to manipulate files within the directory, including executable files like GPMAW3.exe, Fragment.exe, and the uninstaller GPsetup64_17028.exe. An attacker with user-level access can exploit this misconfiguration by replacing or modifying the uninstaller (GPsetup64_17028.exe) with a malicious version. While the application itself runs in the user's context, the uninstaller is typically executed with administrative privileges when an administrator attempts to uninstall the software. By exploiting this flaw, an attacker could gain administrative privileges and execute arbitrary code in the context of the admin, resulting in privilege escalation.

Public exploits

Exploit or proof-of-concept code for this vulnerability is publicly available, which lowers the bar for attackers. Treat it as a reason to patch sooner.

Third-party code, not reviewed by us. Public PoCs are sometimes fake or contain malware. Read the code first and run it only in an isolated lab, against systems you are authorised to test.

GitHub 1 repository

Sources: PoC-in-GitHub, Metasploit Framework, Exploit-DB — updated daily. Only links are listed; no exploit code is hosted here.

References