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OpenAdvisories
Medium · 4.9 CVE-2025-68463 EUVD-2025-204037GHSA-x3vf-39hj-gxr4PYSEC-2026-1221

Biopython is vulnerable to doctype XML external entity (XXE) injection through Bio.Entrez

Published Dec 18, 2025 · Updated May 8, 2026 · Assigned by mitre

Description

Bio.Entrez in Biopython through 186 allows doctype XXE.

Affected products

VendorProductAffectedFixed
Biopython Biopython ≤ 186 —

Fixed in Linux distributions

Distributions backport fixes, so the version that fixes this vulnerability differs per release — upgrade to at least the version shown. From the distributions' security trackers and advisories.

ReleasePackageFixed inAdvisory
Debian 14 python-biopython 1.87+dfsg-1 —
Debian 13 python-biopython No fix yet —
Debian 12 python-biopython No fix yet —
ReleasePackageFixed inAdvisory
Ubuntu 26.10 python-biopython No fix yet —
Ubuntu 26.04 LTS python-biopython No fix yet —
Ubuntu 25.10 python-biopython No fix yet —
Ubuntu 24.04 LTS python-biopython No fix yet —
Ubuntu 22.04 LTS python-biopython No fix yet —
Show 3 more (older releases, extended support, other products)
ReleasePackageFixed inAdvisory
Ubuntu 20.04 LTS python-biopython No fix yet —
Ubuntu 18.04 LTS python-biopython No fix yet —
Ubuntu 16.04 LTS python-biopython No fix yet —
ReleasePackageFixed inAdvisory
openSUSE Tumbleweed python-biopython 1.87-1.1 openSUSE-SU-2026:10537-1
openSUSE Leap 16.0 python-biopython 1.85-bp160.2.1 openSUSE-SU-2026:21169-1

Affected packages

EcosystemPackageAffectedFixedRecord
PyPI biopython <= 1.86 — GHSA-x3vf-39hj-gxr4
PyPI biopython < 1.87 1.87 PYSEC-2026-1221

Advisories 2

References